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History

Date

Event

April, 2003

Company Founded as Maryland Biotherapeutics (MBTI), Robert Ting, Ph.D., named President

March, 2004

Executed license with UMBI for Transition-State Vaccine (TSV) and Genetic Adjuvant technology

May, 2004

MBTI renamed Profectus BioSciences, Inc.

November, 2004

$2.3M in seed money raised (convertible debt)

January, 2005

Operations commenced

April, 2005

Option agreement signed between Profectus BioSciences and Wyeth to evaluate TSV technology ($5.3 million)

July, 2005

Executed license with UMB and UMBI for AIM Therapy Technology

August, 2005

First NIH R01 grant awarded for TSV technology ($350,000)

September, 2005

Profectus names Joe Berardino as CEO.

November, 2005

Material Transfer Agreement signed with Leading Veterinary Company for Genetic Adjuvant technology for veterinary applications e.g. Avian Flu, Rabies, etc.

January, 2006

CRADA signed with NCI for Antiviral MAbs

March, 2006

Profectus honored with Incubator Company of the Year Award (MD)

April, 2006

$5.3M Series A round (including conversion of convertible debt)

October, 2006

First Maryland Industrial Partnership (MIPS) grant awarded ($200,000) for AIM Therapy

January, 2007

Second MIPS grant awarded ($100,000) for Genetic Adjuvant technology

March, 2007

Profectus honored as the Best Academic/ Industry Collaboration Award by the Greater Baltimore Committee.

June, 2007

$3M Private Placement of Convertible Notes and Warrants

June, 2007

First NIH Phase 1 SBIR grant awarded for Genetic Adjuvant technology ($300,000)

July, 2007

Second NIH Phase 1 SBIR grant awarded for AIM Therapy technology ($200,000)

January, 2008

Profectus names Shawn Patrick O’Brien as President, CEO.

June, 2008

Third NIH Phase 1 SBIR grant awarded for Genetic Adjuvant technology ($300,000)

June, 2008

William Haseltine, Ph.D. joins Board of Directors

July, 2008

Fourth NIH Phase 1 SBIR grant awarded for AIM Therapy technology ($200,000)

August, 2008

$4.5M Series B round completed, Profectus moves to 6411 Beckley Street, Baltimore, MD

August, 2008

Thomas Paese, Esq. joins Board of Directors, Jeffrey Stello joins Profectus as Chief Financial Officer

September, 2008

NIH funded HIV Vaccine Design and Development Team (HVDDT) contract awarded for “Therapeutic Immunization Against HIV with Adjuvant-enhanced DNA and Multi-epitope Peptide Vaccines” ($17,572,224)

September, 2008

NIH funded HIV Vaccine Design and Development Team (HVDDT) contract awarded for “HIV-1 Vaccine Candidates Delivered by VSV Vectors” ($4,019,483)

October, 2008

John Eldridge, Ph.D. joins Profectus as Chief Scientific Officer, Vaccines

November, 2008

Profectus executes an Assignment and License Agreement with Wyeth for vaccines against HIV, HCV, HPV, HSV, and Malaria

December, 2008 Profectus receives “People’s Choice” Award at the 2008 Bio-Life-Tech Conference in Baltimore, MD
May, 2009 Tech Council of Maryland selects Profectus as a finalist for Emerging Company of the Year, 2009
June, 2009 US Commerce Association selects Profectus for  Best of Baltimore Award for Commercial Biotechnical Research Company of the Year, 2009
July, 2009 $5M in Series C Venture funding completed
July, 2009 Profectus secures $105K grant from Empire State Development to expand operations to Westchester County, NY
August, 2009 Profectus establishes research collaboration agreement with PATH Malaria Vaccine Initiative (MVI) to evaluate rVSV vector technology
December, 2009 Profectus NY operations moves into 777 Old Saw Mill River Road, Tarrytown, NY
January, 2010 Thomas Pease is appointed Executive Chairman
January, 2010 Frost & Sullivan awards Profectus 2010 Global Entrepreneurial Company of the Year in Vaccines
January, 2010 Baltimore SmartCEO recognizes Profectus as one of the 50 fastest-growing companies in the Greater Baltimore area



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